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. 2023 Apr 6;11(10):2123–2139. doi: 10.12998/wjcc.v11.i10.2123

Table 2.

Diagnostic performance of different non-invasive stress tests

Test Anatomically Significant CAD
Functionally significant CAD
Specificity (95%CI)
Sensitivity (95%CI)
Specificity (95%CI)
Sensitivity (95%CI)
Stress ECG 62 (54-69) 58 (46-69) 73 (55-86) 68 (60-75)
Stress echo 82 (72-89) 85 (80-89)
CCTA 78 (67-86) 97 (93-99) 53 (37-68) 93 (89-96)
SPECT 70 (63-76) 87 (83-90) 83 (71-90) 73 (62-82)
PET 85 (78-90) 90 (78-96) 85 (81-88) 89 (82-93)
Stress CMR 80 (69-88) 90 (83-94) 87 (83-91) 89 (85-92)

CAD: Coronary artery disease; CCTA: Coronary Computed Tomography Angiography; CMR: Cardiac Magnestic Resonance; ECG: Electrocardiogram; echo: echocardiography; SPECT: Single-Photon Emission Computerized Tomography; PET: Positron Emission tomography. The Table 2 summarize the multiple non-invasive stress tests available at this day for coronary artery disease screening. Each exam is characterized by its specificity and sensibility. The exam choice depends on the patient’s clinical situation.