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. Author manuscript; available in PMC: 2023 Apr 26.
Published in final edited form as: Cell Rep. 2023 Feb 23;42(3):112147. doi: 10.1016/j.celrep.2023.112147

Figure 4. DR18 treatment promotes systemic protective immunity in Rag1−/− mice.

Figure 4.

(A) Intracellular staining (left) and ELISA from supernatants (right) of lymphokine activated killer cells stimulated with the cytokines listed.

(B) Quantification of cytospins from peritoneal exudate cells of infected Rag1−/− mice at 7 dpi (top) and representative cytospins (bottom).

(C) Quantification of parasite DNA isolated from lung tissue.

(D) ELISA from serum of Rag1−/− mice at 7 dpi treated as described.

(E) Serum ALT values obtained from Rag1−/− mice at 7 dpi treated as described.

(F) Histology of livers from Rag1−/− mice at 7 dpi treated as described. Black arrows indicate necrotic lesions.

Data are representative of two (A) or 3 (B–F) independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 (Student’s t test, A, ordinary one-way ANOVA with Tukey’s multiple comparisons test, B–D, and Welch’s ANOVA with Dunnett’s multiple comparisons test, E). Data are displayed as mean ± standard error.