Table II.
5-year OS rate | 5-year LRFS rate | |||||
---|---|---|---|---|---|---|
|
|
|||||
Clinicopathological feature | Non-PORT, % | PORT, % | P-value | Non-PORT, % | PORT, % | P-value |
Sex | ||||||
Female | 33.5 | 59.5 | 0.203 | 27.2 | 58.7 | 0.037 |
Male | 34.9 | 45.9 | 0.137 | 27.2 | 45.9 | 0.008 |
Age, years | ||||||
<65 | 34.5 | 48.5 | 0.198 | 25.0 | 47.8 | 0.008 |
≥65 | 33.3 | 59.3 | 0.131 | 34.3 | 59.3 | 0.064 |
Smoking index, pack-year | ||||||
<400 | 40.3 | 57.1 | 0.166 | 33.3 | 56.4 | 0.028 |
≥400 | 23.8 | 41.2 | 0.121 | 15.4 | 41.2 | 0.005 |
Type of surgery | ||||||
Lobectomy | 36.9 | 50.7 | 0.149 | 29.3 | 50.2 | 0.006 |
Pneumonectomy | 0.0 | 50.0 | 0.017 | 0.0 | 50.0 | 0.051 |
Histology | ||||||
SCC | 26.7 | 66.7 | 0.006 | 16.7 | 66.7 | <0.001 |
Non-SCC | 36.9 | 45.6 | 0.560 | 31.9 | 44.8 | 0.170 |
Pathological T stage | ||||||
T1-2 | 35.5 | 51.5 | 0.173 | 29.2 | 50.8 | 0.012 |
T3 | 31.3 | 45.5 | 0.179 | 21.9 | 45.5 | 0.050 |
No. of N2 stations | ||||||
Single | 70.0 | 55.9 | 0.613 | 58.3 | 55.9 | 0.823 |
Multiple | 27.5 | 49.3 | 0.035 | 22.0 | 48.7 | 0.002 |
No. of N2 positive nodes | ||||||
1-3 | 54.2 | 61.0 | 0.778 | 44.7 | 61.0 | 0.213 |
≥4 | 23.0 | 44.6 | 0.019 | 17.2 | 43.8 | 0.001 |
POCT | ||||||
No | 0.0 | 66.7 | 0.083 | 0.0 | 66.7 | 0.083 |
Yes | 35.1 | 50.2 | 0.077 | 27.7 | 49.7 | 0.002 |
Kaplan-Meier analysis followed by log-rank test for various subgroups. P-values were calculated by comparing the PORT and non-PORT groups. OS, overall survival; LRFS, local recurrence free survival; SCC, squamous cell carcinoma; PORT, postoperative radiotherapy; POCT, postoperative chemotherapy.