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. 2023 Apr 26;18:95. doi: 10.1186/s13023-023-02683-9

Table 5.

A total of fifteen pathways contain a high amount of biomarkers for both assays, with at best 46 markers included in one individual pathway model

Pathway ID Title of pathway* ChEBI IDs In PW
WP3604 Biochemical pathways: part I% 46
WP4042 Nucleobase catabolism% 21
WP4225 Pyrimidine metabolism and related diseases 18
WP1936 Transport of inorganic cations/anions and amino acids/oligopeptides% 17
WP4584 Biomarkers for pyrimidine metabolism disorders 17
WP1935 Transport of bile salts and organic acids, metal ions and amine compounds% 17
WP3925 Amino acid metabolism 15
WP4224 Purine metabolism and related disorders 14
WP4082 Nucleotide salvage% 14
WP1938 tRNA aminoacylation% 13
WP1937 Transport of vitamins, nucleosides, and related molecules% 12
WP4792 Purine metabolism 12
WP4595 Urea cycle and associated pathways 11
WP4022 Pyrimidine metabolism 10
WP4583 Biomarkers for urea cycle disorders 10

Medical-Ethical Review * : % indicates which pathways were not found in the top three relevant pathways for any patient