Table 2.
Drug prescription pattern according to chronic kidney disease grade
| CKD Grade | 1 | 2 | 3 | 4 | 5 | p |
|---|---|---|---|---|---|---|
| (n = 3096) | (n = 5420) | (n = 3338) | (n = 482) | (n = 378) | ||
| Aspirin | 1535 (49.6) | 2565 (47.3) | 1461 (43.8) | 218 (45.2) | 187 (49.5) | < 0.001 |
| Clopidogrel | 562 (18.2) | 994 (18.3) | 590 (17.7) | 121 (25.1) | 110 (29.1) | < 0.001 |
| Beta blocker | 1262 (40.8) | 2182 (40.3) | 1342 (40.2) | 168 (34.9) | 136 (36.0) | 0.066 |
| Calcium channel blocker | 644 (20.8) | 1233 (22.7) | 731 (21.9) | 101 (21.0) | 81 (21.4) | 0.314 |
| Digoxin | 456 (14.7) | 1064 (19.6) | 962 (28.8) | 120 (24.9) | 37 (9.8) | < 0.001 |
| Amiodarone | 603 (19.5) | 989 (18.2) | 707 (21.2) | 139 (28.8) | 116 (30.7) | < 0.001 |
| Class Ic AAD∫ | 1317 (42.5) | 1743 (32.2) | 585 (17.5) | 37 (7.7) | 39 (10.3) | < 0.001 |
| Anticoagulants | 1061 (34.3) | 1966 (36.3) | 1224 (36.7) | 134 (27.8) | 62 (16.4) | |
| Warfarin | 871 (82.1) | 1668 (84.8) | 1047 (85.5) | 122 (91.0) | 60 (96.8) | 0.002 |
| NOAC | 190 (17.9) | 298 (15.2) | 177 (14.5) | 12 (9.0) | 2 (3.2) | |
|
Dabigatran Rivaroxaban Apixaban Edoxaban |
107 (56.3) 51 (26.8) 31(16.3) 1 (0.5) |
125 (41.9) 109 (36.6) 64 (21.5) 0 (0.0) |
58 (32.8) 86 (48.6) 32 (18.1) 1 (0.6) |
3 (25.0) 4 (33.3) 5 (41.7) 0 (0.0) |
0 (0.0) 0 (0.0) 2 (100.0) 0 (0.0) |
< 0.001 |
Data are presented as a number (%)
CKD: Chronic kidney disease, AAD: Antiarrhythmic drug, NOAC: Non-vitamin K oral anticoagulants