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. 2023 Feb 19;10(12):2207499. doi: 10.1002/advs.202207499

Figure 5.

Figure 5

Deficiency of T‐bet, Eomes, or IFN‐γ in NK cells attenuates the antitumor function of CD8+ T cells. A) MC38 tumor growth in CD8+ cell‐depleted or control Tbx21 WT/ WT mice or Tbx21 ΔNK/ΔNK mice. B) MC38 tumor growth in CD8+ cell‐depleted or control Eomes WT/ WT mice or Eomes ΔNK/ΔNK mice. C) MC38 tumor growth in CD8+ cell‐depleted or control Ifng WT/ WT mice or Ifng ΔNK/ΔNK mice. A–C) Data are mean values ± SEM representative of two independent experiments (n = 6). **p < 0.005, ***p < 0.001, ****p < 0.0001 (two‐way ANOVA).