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. Author manuscript; available in PMC: 2023 Apr 26.
Published in final edited form as: J Control Release. 2018 Nov 8;292:221–234. doi: 10.1016/j.jconrel.2018.11.010

Figure 4 ∣. Three-dimensional final distribution of drugs in tumor tissues as a function of the trans-endothelial transport probability and tissue diffusivity of drugs in the tumor.

Figure 4 ∣

A: A heat map plot shows the drug concentration inside the tissue and vasculature for a range of trans-endothelial transport probabilities and tissue diffusivities. The optimal range of parameters is highlighted by a green box. B: Analysis of the drug distribution across the tumor tissue allows precise spatial mapping of the therapeutic efficiency.