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. Author manuscript; available in PMC: 2023 Apr 26.
Published in final edited form as: Transl Res. 2020 Mar 16;220:98–113. doi: 10.1016/j.trsl.2020.03.009

Figure 2.

Figure 2.

Sharma et al.28 formulated HDTs for tuberculosis. (A) Poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs) encapsulating magainin-I analog peptide (MIAP) which are coated with mannitol to form larger (B) MIAP porous aggregates of PLGA NPs. (C) Schematic depicting fabrication of MIAP porous microparticles (MPs) via spray freeze drying. (D) Panel demonstrating co-localization of M. tb (green) with acidic lysosome (red) in MIAP and MIAP MP groups compared to controls (untreated, isoniazid (INH)) in RAW macrophages.28