Table 5.

Top fifty gene sets enriched in phenotype EGR3.

rank	gene set	size	ES	NES	FDR q-val	rank at max
1	REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	114	0.41	2.96	0.05	4040
2	LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN	164	0.41	2.79	0.05	1819
3	GNF2_PTPRC	67	0.62	2.74	0.05	2657
4	WP_B_CELL_RECEPTOR_SIGNALING_PATHWAY	97	0.55	2.73	0.05	3716
5	GOBP_POSITIVE_REGULATION_OF_INTERFERON_BETA_PRODUCTION	37	0.52	2.73	0.05	2366
6	GOBP_ATP_METABOLIC_PROCESS	201	0.38	2.71	0.05	4185
7	HP_MYOCLONUS	348	0.42	2.71	0.05	4350
8	YAP1_UP	43	0.51	2.7	0.05	4532
9	GOBP_INTERFERON_BETA_PRODUCTION	55	0.51	2.67	0.05	2366
10	REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA	68	0.46	2.66	0.05	2201
11	ALCALA_APOPTOSIS	85	0.41	2.66	0.05	2052
12	DER_IFN_BETA_RESPONSE_UP	103	0.43	2.66	0.05	3809
13	BROWNE_INTERFERON_RESPONSIVE_GENES	64	0.57	2.66	0.05	3071
14	GNF2_VAV1	35	0.58	2.66	0.05	3195
15	HP_BRITTLE_HAIR	40	0.52	2.65	0.05	1355
16	GOBP_DEFENSE_RESPONSE_TO_SYMBIONT	257	0.43	2.63	0.05	3422
17	NGUYEN_NOTCH1_TARGETS_DN	82	0.5	2.62	0.05	3342
18	PID_BCR_5PATHWAY	63	0.54	2.61	0.05	3716
19	HP_CHOREOATHETOSIS	99	0.41	2.61	0.05	3007
20	REACTOME_SARS_COV_INFECTIONS	355	0.34	2.61	0.05	6457
21	HP_MEMORY_IMPAIRMENT	139	0.43	2.61	0.05	3896
22	GOBP_RESPONSE_TO_VIRUS	347	0.44	2.59	0.05	3494
23	HALLMARK_INTERFERON_ALPHA_RESPONSE	96	0.46	2.56	0.05	4121
24	GOBP_REGULATION_OF_INTRACELLULAR_TRANSPORT	320	0.35	2.56	0.05	6271
25	HP_NEOPLASM_OF_THE_LIVER	124	0.49	2.55	0.05	5154
26	WP_APOPTOSIS	85	0.46	2.55	0.05	3921
27	REACTOME_TAK1_DEPENDENT_IKK_AND_NF_KAPPA_B_ACTIVATION	43	0.53	2.54	0.05	2041
28	HP_ECTOPIC_CALCIFICATION	209	0.44	2.54	0.05	3466
29	HP_ABNORMAL_CNS_MYELINATION	307	0.36	2.53	0.05	6718
30	BOQUEST_STEM_CELL_DN	206	0.51	2.52	0.05	2711
31	HP_WEAKNESS_DUE_TO_UPPER_MOTOR_NEURON_DYSFUNCTION	469	0.39	2.52	0.05	4528
32	HP_ACUTE_LEUKEMIA	105	0.41	2.52	0.05	5158
33	REACTOME_RHO_GTPASE_CYCLE	436	0.37	2.52	0.05	4897
34	HOEBEKE_LYMPHOID_STEM_CELL_UP	92	0.44	2.51	0.05	2556
35	GOBP_REGULATION_OF_VIRAL_GENOME_REPLICATION	82	0.45	2.51	0.05	3466
36	REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING	144	0.39	2.51	0.05	2041
37	REACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA	62	0.41	2.51	0.05	2201
38	WANG_TARGETS_OF_MLL_CBP_FUSION_UP	43	0.49	2.51	0.05	4346
39	GYORFFY_DOXORUBICIN_RESISTANCE	33	0.65	2.51	0.05	2036
40	HALLMARK_ALLOGRAFT_REJECTION	179	0.55	2.51	0.05	3064
41	GOBP_ACTIVATION_OF_GTPASE_ACTIVITY	109	0.49	2.51	0.05	2641
42	GNF2_MYD88	59	0.5	2.49	0.05	2926
43	MODULE_256	58	0.46	2.49	0.05	4870
44	HP_CHRONIC_DIARRHEA	75	0.48	2.48	0.05	3992
45	HP_ABNORMALITY_OF_CARDIOVASCULAR_SYSTEM_ELECTROPHYSIOLOGY	449	0.4	2.48	0.05	3898
46	YAGI_AML_WITH_T_8_21_TRANSLOCATION	351	0.39	2.48	0.05	5568
47	HP_PREMATURE_GRAYING_OF_HAIR	39	0.51	2.48	0.05	1796
48	HP_CNS_DEMYELINATION	39	0.61	2.48	0.05	4378
49	HP_SHORTENING_OF_ALL_DISTAL_PHALANGES_OF_THE_FINGERS	39	0.52	2.48	0.05	5023
50	GOBP_REGULATION_OF_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY	122	0.45	2.48	0.05	4933

ES enrichment score, NES nominal ES, FDR false discovery rate.