Table 4. Comparison of treatment strategy between open and closed surgical intensive care unit.
| Variable | OSICU group (n = 191) | CSICU group (n = 560) | p |
|---|---|---|---|
| Fluid resuscitation | |||
| 1st day of ICU admission | |||
| Total Intake (ml) | 3439.5 ± 1889.50 | 3836.1 ± 2030.54 | < 0.05 |
| Net I/O on 1st day of ICU admission (ml/kg/day) | 27.9 ± 25.40 | 33.7 ± 38.45 | < 0.05 |
| 20% albumin 100 ml (ml) | 29.3 ± 56.93 | 40.9 ± 67.59 | < 0.05 |
| 2nd day of ICU admission | |||
| Total Intake (ml) | 2752.0 ± 988.31 | 2854.4 ± 1145.75 | 0.271 |
| Net I/O the 2nd day of ICU admission (ml/kg/day) | 12.3 ± 19.38 | 11.4 ± 23.45 | 0.629 |
| 20% albumin 100 ml (ml) | 38.7 ± 62.97 | 49.3 ± 60.11 | < 0.05 |
| Vasopressors | |||
| Use of norepinephrine (%) | 11 (5.8) | 233 (41.6) | < 0.05 |
| Maximum norepinephrine infusion rate (μg/kg/min) | 0.13 ± 0.146 | 0.08 ± 0.107 | 0.112 |
| Use of vasopressin (%) | None | 44 (7.9) | < 0.05 |
| Maximum vasopressin infusion rate (IU/min) | None | 0.03 ± 0.046 | |
| Use of epinephrine (%) | None | 18 (3.2) | < 0.05 |
| Maximum epinephrine infusion rate (μg/kg/min) | None | 0.13 ± 0.099 | |
| Analgesics and sedatives (%) | |||
| Fentanyl | 101 (52.9) | 482 (86.1) | < 0.05 |
| Remifentanil | 36 (18.8) | 151 (27.0) | < 0.05 |
| Propofol | 7 (3.7) | 34 (6.1) | 0.206 |
| Dexmedetomidine | 2 (1.0) | 401 (71.8) | < 0.05 |
| Catheterization | |||
| Central catheter (%) | 4 (2.1) | 20 (3.6) | 0.316 |
| Location of central catheter (%) | |||
| Subclavian vein | 2 (50.0) | 7 (35.0) | |
| Internal jugular vein | 2 (50.0) | 9 (45.0) | 0.601 |
| Femoral vein | None | 4 (20.0) | |
| Arterial cannulation (%) | 128 (67.0) | 501 (89.5) | < 0.05 |
| Transfusion | |||
| 1st day of ICU admission | |||
| Red blood cell (unit) | 0.7 ± 2.68 | 1.1 ± 2.49 | 0.060 |
| Fresh frozen plasma (unit) | 0.2 ± 1.53 | 0.4 ± 1.44 | 0.298 |
| Platelet concentration (unit) | 0.3 ± 2.45 | 0.1 ± 0.77 | 0.362 |
| 2nd day of ICU admission | |||
| Red blood cell (unit) | 0.2 ± 0.60 | 0.3 ± 0.84 | 0.134 |
| Fresh frozen plasma (unit) | 0.1 ± 0.57 | 0.0 ± 0.35 | 0.241 |
| Platelet concentration (unit) | 0.1 ± 0.85 | 0.1 ± 0.54 | 0.426 |
| Others | |||
| Antacid (%) | 133 (69.6) | 543 (97.0) | < 0.05 |
| Low-molecular-weight heparin for DVT prophylaxis (%) | 40 (20.9) | 107 (19.1) | 0.581 |
| Intermittent pneumatic compression for DVT prophylaxis (%) | 1 (0.5) | 518 (92.5) | < 0.05 |
| Benzydamine hydrochloride or chlorhexidine gluconate solution for oral care (%) | 10 (5.2) | 539 (96.3) | < 0.05 |
| High-flow nasal cannula (%) | None | 212 (37.9) | < 0.05 |
OSICU, open surgical intensive care unit; CSICU, closed surgical intensive care unit; ICU, intensive care unit; DVT, deep vein thrombosis