Table 4.

Plasma glucose and urea concentration of rumen-cannulated Bos indicus Nellore steers receiving forage-based diets supplemented or not (CON, n = 8) with narasin (NAR, n = 8), lasalocid (LAS; n = 8), or virginiamycin (VRM; n = 8) for 140 days (Exp. 1)

	Treatments1					P-value2
Item3	CON	NAR	LAS	VRM	SEM	Treatment	Day	T × D
Glucose, mg/dL	69.37	69.30	68.63	70.53	1.52	0.76	<0.01	0.51
Urea, mg/dL	32.46	33.74	32.11	34.56	1.36	0.53	<0.01	0.60

¹CON, no feed additives; NAR, inclusion of 13 mg/kg of dry matter (DM) of narasin (Zimprova; Elanco Animal Health, São Paulo, SP, Brazil); LAS, inclusion of 20 mg/kg of DM of lasalocid (Taurotec; Zoetis, Sao Paulo, SP, Brazil; n = 8); VRM, inclusion of 20 mg/kg of DM of virginiamycin (V-Max; Phibro Animal Health Corporation, Guarulhos, SP, Brazil; n = 8). Within rows, values with different superscripts differ (P ≤ 0.05).

² P-value for treatment, day, and treatment × day interaction (T × D).

³Blood samples were collected on day 0 (immediately prior to the beginning of the experimental period and first treatment offer), 28, 56, 84, 112, and 140 of the experimental period and 6 h after feeding, via coccygeal venipuncture into commercial vacutainer collection tubes with glycolytic inhibitor and anticoagulant K3EDTA (Vacuette; Greiner Bio-One, Americana, SP, Brazil).