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. 2023 Mar 8;616(7958):707–711. doi: 10.1038/s41586-023-05773-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — The blue line is the trajectory of junior engineer #3 alone, with cost-to-target of $190,000. The orange line on the secondary axis is the median cost of HF–CL (using Algo3) at the transfer points indicated (Extended Data Table 3). The V-shaped dependence of cost-to-target is apparent. HF–CL provides an impressive cost savings at point B′ compared with the junior engineer alone. However, the cost-to-target is still markedly higher (about double) than HF–CL using the expert–Algo 3 combination.