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. 2023 Apr 12;616(7958):814–821. doi: 10.1038/s41586-023-05922-y

Extended Data Fig. 3. Consistency of RNA Pol-II speed changes.

Extended Data Fig. 3

(a) Change of elongation rate with aging or senescence in introns of C. elegans, D. melanogaster, M. musculus and H. sapiens, before and after filtering for introns that consistently change in speed in all replicates. (b) Change of elongation rate with mutations that slow down the speed of RNA-Pol-II in introns of C. elegans and D. melanogaster before and after filtering for introns that consistently change in speed in all replicates. (c) Comparison of the change of elongation rate with aging between IMR90 and HUVEC using the same introns.