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. 2023 Apr 12;616(7958):764–773. doi: 10.1038/s41586-023-05927-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 5 — a. Expression levels (in label-free quantification intensity, LFQ intensity) of cell-enriched markers identified in each BioID2 construct (n = 4 experimental runs with 8 mice in each run). Proteins in this analysis represent proteins that were enriched (Log2FC > 1 versus GFP controls). The mean LFQ value and SEM are shown. b. Pie chart of PANTHER pathway analysis terms for “biological processes”. Pie chart shows the number of proteins found for each term from the 332 Astro BioID2 proteins. c. As in b, but for the 434 Neuro BioID2 proteins. d. As in b, but for 310 Astro Lck-BioID2 proteins. e. As in b, but for the 1672 Neuro Lck-BioID2 proteins. f. Bar graph denotes the number of calcium dependent vesicle release protein isoforms detected in each BioID2 construct experiment. g. Bar graph denotes the number of lipid metabolism related proteins that were detected in each BioID2 construct experiment.