Table 1:
Baseline clinical characteristics by age for 902 participants.
| Characteristics* | Overall, n=902 | 0 to <7 yrs, n=264 | ≥7 to <13 yrs, n=317 | ≥13 to ≤18 yrs, n=321 |
|---|---|---|---|---|
| Median age, years Male sex | 10.73 [6.21, 14.40] 64% (573) | 4.62 [3.62, 5.60] 70% (184) | 10.19 [8.73, 11.40] 62% (195) | 15.25 [14.23, 16.16] 60% (194) |
| BMI percentile | 69 [39, 91] | 66 [38, 86] | 69 [41, 91] | 72 [42, 93] |
| Obesity (BMI >95th percentile) | 18% (162) | 14% (37) | 18% (58) | 21% (67) |
| Low birth weight (<2500 grams) | 18% (155) | 22% (54) | 18% (53) | 16% (48) |
| Premature birth (<36 weeks) | 12% (108) | 19% (49) | 10% (29) | 10% (30) |
| iGFR, ml/min/1.73m2 | 49.0 [37.0, 65.1] | 49.0 [35.9, 60.8] | 47.7 [37.3, 61.6] | 52.9 [37.3, 71.5] |
| eGFR, ml/min/1.73m2 | 49.9 [36.6, 64.4] | 49.7 [36.0, 62.4] | 48.5 [37.6, 62.0] | 51.5 [36.8, 68.4] |
| Proteinuria (UPC) | 0.34 [0.13, 0.95] | 0.33 [0.15, 0.72] | 0.24 [0.10, 0.93] | 0.45 [0.15, 1.35] |
| Glomerular diagnosis | 28% (252) | 9% (24) | 24% (77) | 47% (151) |
| CKD duration at enrollment, years | 7 [4, 12] | 4 [3, 5] | 9 [7, 11] | 13 [3, 15] |
*
Reported as median [IQR] for continuous variables and percent (n) for categorical variables. Missing data includes birth weight, n=61; premature, n=33; iGFR, n=112; CKD onset date, n=8. BMI body mass index, iGFR iohexol glomerular filtration rate, eGFR estimated glomerular filtration rate, UPC urine protein to creatinine ratio, CKD chronic kidney disease.