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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Exp Eye Res. 2023 Mar 24;230:109456. doi: 10.1016/j.exer.2023.109456

Figure 3: Collagen XII regulates tissue repair during early stages of repair (day 10) and is present in the provisional matrix that bridges both ends of the wound.

Figure 3:

(A) Collagen XII expression is noted in the regenerated tissue bridging ends of the keratotomy injury during early tissue repair. (B) Higher magnification image shows collagen XII expression in regenerated matrix where migrating fibroblasts are secreting collagen XII-note collagen XII around cells. (C) Control, Col12a1−/− mouse cornea show epithelialized larger wound and no expression of collagen XII. (D) A poorly healed wound in higher magnification- note no stromal cells in area. Bar 25 μm.