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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Exp Eye Res. 2023 Mar 24;230:109456. doi: 10.1016/j.exer.2023.109456

Figure 5: Collagen XII regulates wound maturation and deposition of a provisional matrix during tissue repair.

Figure 5:

(A) Histology sections showed regenerated collagen in the injury area in WT cornea, shown in green by SHG imaging. LTBP-1 expression is noted, marked by asterisk, filling in the wound where fibrillogenesis is occurring. Areas of colocalization of LTBP-1 expression and fibrillogenesis are noted in the maturing wound. (B) Immature open wound with no regenerated collagen in the wound in the absence of collagen XII. There is no LTBP-1 expression in the open wound in the collagen XII deficient cornea. Dashed line demarcates area of open wound. Bar 25 μm.