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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Exp Eye Res. 2023 Mar 24;230:109456. doi: 10.1016/j.exer.2023.109456

Figure 6: Transmission electron microscopy microphotographs demonstrating the role of collagen XII in regulating fibrillogenesis and wound maturation 7 – 10 days pot injury.

Figure 6:

(A) Activated fibroblasts in the WT corneal matrix show significant fibrillogenesis and activated fibroblasts in the maturing wound. A1: Normal alignment of fibrils and lamellae in WT corneas. (B) Larger and apparently activated fibroblasts in the collagen XII deficient matrix in a regenerated matrix with decreased fibrillogenesis in the maturing wound. B1: Higher magnification confirms poor fibrillogenesis and poor fibril organization in a regenerated matrix without collagen XII. Bar 500 nm.