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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Adv Drug Deliv Rev. 2023 Mar 17;196:114776. doi: 10.1016/j.addr.2023.114776

Fig. 5. Examples of in vitro killing or growth inhibition experiments on fungal pathogens by DectiSomes.

Fig. 5.

(A). A hyphal length extension assay demonstrating DEC1-AmB-LLs selectively and quantitatively inhibited the in vitro growth A. fumigatus relative to untargeted control liposomes, AmB-LLs and BSA-AmB-LLs. (B). A Cell Titer Blue electrochemical reduction assay demonstrating DEC2-AmB-LLs inhibited the growth of or killed in vitro grown A. fumigatus. (C). A Cell Titer Blue assay demonstrating DEC2-AmB-LLs inhibited or killed in vitro grown C. albicans. (D). DC-SIGN isoform coated DCS12-AmB-LLs killed or inhibited the growth of C. neoformans in liquid media as quantified by counting colony forming units (CFUs). These data are from replicates of experiments not shown in the original publications [107,215,219,220].