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PKNOX2 inactivates the PI3K/AKT/mTOR signaling. Western blot analysis of PI3K p85α, PI3K p110α, p-AKT, AKT, p-mTOR and mTOR in (A) PKNOX2-silenced A549 cells and (B) in PKNOX2-overexpressing HCC827 cells. *P<0.05 and **P<0.01 vs. si-NC or vector. PKNOX2, PBX/knotted 1 homeobox 2.
