Table I.
Association between PKNOX2 expression and clinicopathological features in LC.
| Expression of PKNOX2 | ||||
|---|---|---|---|---|
| Characteristics | Patients (n=60) | High (n=30) | Low (n=30) | P-value |
| Sex | 0.795 | |||
| Male | 33 | 17 | 16 | |
| Female | 27 | 13 | 14 | |
| Age, years | 0.781 | |||
| <60 | 19 | 10 | 9 | |
| >60 | 41 | 20 | 21 | |
| Pathological type | >0.99 | |||
| Adenocarcinoma | 55 | 28 | 27 | |
| Squamous cell carcinoma | 5 | 2 | 3 | |
| Tumor invasion | <0.0001a | |||
| T1 | 32 | 25 | 7 | |
| T2 | 25 | 5 | 20 | |
| T3 | 3 | 0 | 3 | |
| Lymph node metastasis | 0.0057a | |||
| N0 | 41 | 26 | 15 | |
| N1 | 9 | 3 | 61 | |
| N2+N3 | 10 | 1 | 9 | |
| Distant metastasis | >0.99 | |||
| M0 | 60 | 30 | 30 | |
| M1 | 0 | 0 | 0 | |
| TNM stage | 0.0003a | |||
| I | 37 | 26 | 11 | |
| II | 12 | 3 | 9 | |
| Ⅲ + Ⅳ | 11 | 1 | 10 | |
aP<0.01. PKNOX2, PBX/knotted 1 homeobox 2.