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. 2023 Apr 13;14:1140856. doi: 10.3389/fphys.2023.1140856

TABLE 3.

Serum SSC5D levels were highly associated with the risk factors of HF.

Unadjusted p-Value Model 1 p-Value Model 2 p-Value
OR (95% CI) OR (95% CI) OR (95% CI)
logSSC5D (per SD) 3.23 (2.32–4.50) <0.001 3.60 (2.53–5.11) <0.001 3.40 (2.10–5.51) <0.001
SSC5D tertiles 3.31 (2.35–4.66) <0.001 4.16 (2.77–6.26) <0.001 3.41 (2.05–5.67) <0.001
Tertile 1 1 (referent) 1 (referent) 1 (referent)
Tertile 2 3.61 (1.87–6.97) <0.001 4.90 (2.38–10.10) <0.001 4.03 (1.71–9.48) 0.001
Tertile 3 11.02 (5.53–21.97) <0.001 17.70 (7.78–40.24) <0.001 11.83 (4.30–33.09) <0.001

SSC5D concentration was normalized by log10 transformation to obtain normality and divided into tertiles.

Model 1: Adjusted for age and sex.

Model 2: Adjusted for sex, age, BMI, diabetes mellitus, hypercholesterolemia, hypertension, hemoglobin, creatinine, low-density lipoprotein cholesterol, hypersensitive C-reactive protein, blood urea nitrogen, HbA1c, and estimated glomerular filtration rate.