Table 1.

Recent clinical trial records on RNSM from Clinicaltrial.gov website. ^†Status of the record is as of April 4th, 2023

Clinicaltrial.gov Identifier	Sponsor	Estimated enrollment	Primary outcome	Indication	Allocation	Status†
NCT03440398	European Institute of Oncology (Italy)	82	Patient satisfaction (BREAST-Q)	Breast cancer or prophylaxis	Randomized	Active, not recruiting
NCT03892980	Intuitive Surgical (USA)	145	Conversion to open NSM, incidence of adverse events	Prophylaxis only	Single arm	Recruiting
NCT04108117	Severance Hospital (South Korea)	300	Locoregional recurrence-free survival	Breast cancer or prophylaxis	Single arm, retrospective pooled analysis	Active, not recruiting
NCT04537312	The Ohio State University (USA)	20	Feasibility of en bloc removal of breast	Breast cancer or prophylaxis	Single arm	Recruiting
NCT04585074	Severance Hospital (South Korea)	2000	Postoperative complication	Breast cancer or prophylaxis	Single arm	Recruiting
NCT04866992	University of Texas Southwestern Medical Center (USA)	10	Feasibility of en bloc removal of breast	Breast cancer or prophylaxis	Single arm	Completed
NCT05245812	University of Texas Southwestern Medical Center (USA)	90	Completion with SP system, periop complications	Breast cancer or prophylaxis	Single arm	Recruiting
NCT05251285	Intuitive Surgical (France, Italy)	50	Intraop and postop complications	Porphylaxis	Single arm	Recruiting
NCT05448963	Chang Gung Memorial Hospital (Taiwan)	30	Surgical performance of SP system (conversion to open, addition of ports)	Breast cancer or prophylaxis	Single arm	Recruiting
NCT05490433	Yonsei University (South Korea)	790	5-year disease-free survival rate	Stage 0-III breast cancer	Randomized	Not yet recruiting
NCT05720039	Intuitive Surgical (USA)	200	Conversion to open, adverse event, positive surgical margin	Breast cancer or prophylaxis	Randomized	Not yet recruiting