Table 1.
Laboratory findings during the disease course
| Day 1 | Day 21 | Day 102 | Day 288 | Day 511 | |
|---|---|---|---|---|---|
| Blood test | |||||
| Albumin (g/dL) | 2.0 | 4.0 | 3.4 | 3.7 | 4.1 |
| Aspartate aminotransferase (IU/L) | 33 | 11 | 22 | 13 | 14 |
| Alanine transaminase (IU/L) | 21 | 17 | 38 | 11 | 10 |
| Urea nitrogen (mg/dL) | 16.1 | 20.9 | 27.9 | 14.5 | 21.0 |
| Creatinine (mg/dL) | 1.52 | 1.24 | 1.30 | 1.34 | 1.41 |
| Urine acid (mg/dL) | 5.3 | 3.4 | 5.8 | 5.9 | 6.1 |
| Sodium (mEq/L) | 144 | 137 | 142 | 142 | 145 |
| Potassium (mEq/L) | 3.8 | 4.1 | 4.1 | 3.7 | 3.7 |
| Chloride (mEq/L) | 107 | 103 | 107 | 108 | 109 |
| Corrected calcium (mEq/L) | 10.4 | 9.4 | 9.6 | 9.7 | 9.8 |
| C-reactive protein (mg/dL) | 26.06 | 0.14 | 0.03 | 0.27 | 0.56 |
| Hemoglobin A1c (%) | 5.9 | 5.4 | |||
| IgG (mg/dL) | 1892.0 | 272.0 | 687.0 | ||
| IgA (mg/dL) | 296.0 | 92.0 | 195.0 | ||
| IgM (mg/dL) | 89.0 | 72.0 | 57.0 | ||
| IgG4 (mg/dL) | 209 | 55 | |||
| Complement C3 (mg/dL) | 108.0 | 35.0 | 95.0 | ||
| Complement C4 (mg/dL) | 20.9 | 9.8 | 25.4 | ||
| Rheumatoid factor (IU/mL) | 35.6 | 48.0 | |||
| Anti-nuclear antibody titer | Negative | Negative | |||
| PR3-ANCA (IU/mL) | Negative | Negative | Negative | ||
| MPO-ANCA (IU/mL) | 19.7 | 2.4 | < 0.5 | 10.0 | 3.6 |
| Anti-GBM antibody (EU) | 22.7 | 1.0 | 0.7 | < 1.5 | < 1.5 |
| ASO (IU/mL) | 14 | 53 | |||
| ASK (IU/mL) | < 40 | < 40 | |||
| White blood cell (/μL) | 11,570 | 8520 | 5190 | 9850 | 19,020 |
| Hemoglobin (g/dl) | 8.6 | 8.3 | 9.2 | 11.1 | 12.7 |
| Platelet (× 103/μL) | 518 | 147 | 209 | 22.1 | 23.3 |
| Spot urine urinalysis | |||||
| Specific gravity | 1.005 | 1.011 | 1.013 | 1.007 | 1.016 |
| Blood | 3+ | 3+ | 1+ | 3+ | 2+ |
| Protein | (−) | 1 + | (−) | (−) | (−)〜(±) |
| RBCs (/HPF) | 20–29 | 50–99 | 5–9 | 50–99 | 1–4 |
| Protein (g/gCre) | 0.19 | 1.15 | 0.26 | 0.12 | 0.18 |
Shown are blood and urine data at admission (day 1), 3 weeks after admission (day 21), during remission (day 102), at relapse (day 288), and at time of writing (day 511)