TABLE 3.
Tumor grade correlation between D&C, Hys, IFS, parallel mode (D&C + IFS), parallel mode (Hys + IFS), and final surgical specimen.
| High‐grade EA | Postoperative PS | Cronbach's α | Kappa | Accuracy% (95% CI) | Sensitivity % (95% CI) | Specificity % (95% CI) | PPV % (95% CI) | NPV % (95% CI) | ||
|---|---|---|---|---|---|---|---|---|---|---|
| No | Yes | Total | ||||||||
| D&C | ||||||||||
| No | 508 | 56 | 564 | 0.385 | 0.226 | 89.33 (86.46–91.66) | 16.42 (8.87–27.91) | 98.83 (97.34–99.52) | 64.71 (38.62–84.74) | 90.07 (87.23–92.35) |
| Yes | 6 | 11 | 17 | |||||||
| Total | 514 | 67 | 581 | |||||||
| D&C + IFS in parallel | ||||||||||
| No | 490 | 24 | 514 | 0.746 | 0.595 | 91.74 (89.12–93.79) | 64.18 (51.47–75.26) | 95.33 (93.03–96.92) | 64.18 (51.47–75.26) | 95.33 (93.03–96.92) |
| Yes | 24 | 43 | 67 | |||||||
| Total | 514 | 67 | 581 | |||||||
| Hys | ||||||||||
| No | 507 | 58 | 565 | 0.321 | 0.180 | 88.81 (85.89–91.20) | 13.43 (6.70–24.47) | 98.64 (97.09–99.40) | 56.25 (30.55–79.25) | 89.73 (86.86–92.05) |
| Yes | 7 | 9 | 16 | |||||||
| Total | 514 | 67 | 581 | |||||||
| Hys + IFS in parallel | ||||||||||
| No | 489 | 25 | 514 | 0.733 | 0.578 | 91.39 (88.73–93.48) | 62.69 (49.97–73.95) | 95.14 (92.81–96.77) | 62.69 (49.97–73.95) | 95.14 (92.81–96.77) |
| Yes | 25 | 42 | 67 | |||||||
| Total | 514 | 67 | 581 | |||||||
| IFS | ||||||||||
| No | 496 | 28 | 524 | 0.739 | 0.585 | 92.08 (89.50–94.08) | 58.21 (45.54–69.94) | 96.50 (94.42–97.85) | 68.42 (54.62–79.73) | 94.66 (92.28–96.36) |
| Yes | 18 | 39 | 57 | |||||||
| Total | 514 | 67 | 581 | |||||||
Abbreviations: D&C, diagnostic curettage; IFS, intraoperative frozen section; High‐grade EA, endometrioid adenocarcinoma with grade 3; Hys, hysteroscope; PS, paraffin section.