TABLE 6.
Univariate logistic regression analysis of “IFS under‐diagnoses or not” and “IFS over‐diagnoses or not” in detecting high‐grade.
| IFS detecting high‐grade EA | Accurate‐diagnoses | Under‐diagnoses | Under‐diagnoses or not | Over‐diagnoses | Over‐diagnoses or not | ||
|---|---|---|---|---|---|---|---|
| OR 95% CI | p Value | OR 95% CI | p Value | ||||
| Menopause | |||||||
| Pre | 1,215 (42.77) | 75 (38.07) | 1 | 0.198 | 43 (53.75) | 1 | 0.052 |
| Post | 1,626 (57.23) | 122 (61.93) | 1.215 (0.903–1.636) | 37 (46.25) | 0.643 (0.412–1.004) | ||
| Atypical hyperplasia | |||||||
| No | 2,368 (82.94) | 170 (85.43) | 1 | 0.366 | 68 (83.95) | 1 | 0.812 |
| Yes | 487 (17.06) | 29 (14.57) | 0.829 (0.553–1.244) | 13 (16.05) | 0.930 (0.510–1.696) | ||
| Uterine diseases (myoma or adenomyosis) | |||||||
| No | 2,530 (88.62) | 180 (90.45) | 1 | 0.429 | 65 (80.25) | 1 | 0.023 |
| Yes | 325 (11.38) | 19 (9.55) | 0.822 (0.505–1.337) | 16 (19.75) | 1.916 (1.096–3.351) | ||
| Caesarean section | |||||||
| No | 2,542 (89.48) | 173 (87.82) | 1 | 0.466 | 70 (87.50) | 1 | 0.572 |
| Yes | 299 (10.52) | 24 (12.18) | 1.179 (0.757–1.838) | 10 (12.50) | 1.215 (0.619–2.381) | ||
| Abortion history | |||||||
| No | 1,185 (41.71) | 87 (44.16) | 1 | 0.500 | 34 (42.50) | 1 | 0.888 |
| Yes | 1,656 (58.29) | 110 (55.84) | 0.905 (0.676–1.210) | 46 (57.50) | 0.968 (0.618–1.518) | ||
| Deep MI | |||||||
| No | 2,476 (86.73) | 162 (81.41) | 1 | 0.036 | 71 (87.65) | 1 | 0.808 |
| Yes | 379 (13.27) | 37 (18.59) | 1.492 (1.027–2.167) | 10 (12.35) | 0.920 (0.470–1.800) | ||
Abbreviations: IFS, intraoperative frozen section; High‐grade EA, endometrioid adenocarcinoma with grade 3; MI, myometrial invasion; OR, dominance ratio.