TABLE 7.
Therapeutic response by immune‐related AEs
| Immune‐related liver injury | Immune‐related endocrine dysfunction | |||||
|---|---|---|---|---|---|---|
| Yes (n = 30) | No (n = 233) | p value | Yes (n = 29) | No (n = 234) | p value | |
| CR | 1 (3.3%) | 12 (5.2%) | 0.901 | 1 (3.4%) | 12 (5.1%) | 0.265 |
| PR | 10 (33.3%) | 61 (26.2%) | 11 (37.9%) | 60 (25.6%) | ||
| SD | 14 (46.7%) | 118 (50.6%) | 15 (51.7%) | 117 (50.0%) | ||
| PD | 5 (16.7%) | 42 (18.0%) | 2 (6.9%) | 45 (19.2%) | ||
| ORR | 36.7% | 31.3% | 0.540 | 41.4% | 30.8% | 0.292 |
| DCR | 83.3% | 82.0% | 1.000 | 93.1% | 80.8% | 0.126 |
Abbreviations: AE, adverse event; CR, complete response; DCR; disease control rate; ORR, overall response rate; PD, progressive disease; PR, partial response; SD, stable disease.