FIG 2.

MCPyV infection induces the expression of IFN-β and other innate immune cytokines. (A) mRNA levels of IFN-β, IFN-λ1, and other cytokines were measured by RT-qPCR in HDFs infected with MCPyV on day 6 postinfection. The values for the mRNA molecules in mock-infected HDFs were set as 1. (B) mRNA levels of IFN-β, IFN-λ1, OAS1, and LT were measured by RT-qPCR in HDFs infected with MCPyV on day 3 to day 7 postinfection. One of the values for mock-infected HDFs on day 3 was set as 1. No LT was detected in the mock-infected HDFs. Error bars indicate standard deviations from three independent experiments. ***, P < 0.001; **, P < 0.01; *, P < 0.05; ns, not significant.