Table 1.
Dose | ID | EIA | ||||
---|---|---|---|---|---|---|
Cortisol | Corticosterone | 5α-Pregnane | Oxoaetio | Oxoaetio | ||
Cholanolone I | Cholanolone II | |||||
Low | F1 | −42 | −7 | 40 ^ | 174 ^ | 11 |
F2 | 60 ^ | −23 * | 46 * | 26 * | 38 * | |
F3 | 325 | 193 | 19 | 130 * | −23 * | |
High | F5 | 29 | −13 | −15 | −5 | 170 |
F6 | 106 * | 105 * | −2 * | 28 * | 71 * | |
Low | M1 | 17 ^ | 69 ^ | 115 ^ | −5 ^ | 26 |
M2 | 4 * | −58 * | 131 * | 88 * | 88 * | |
M3 | 1545 ^ | 457 ^ | 338 ^ | 424 ^ | 367 ^ | |
High | M4 | 261 | 91 | 295 ^ | 73 ^ | 71 |
M5 | 995 ^ | 612 ^ | 113 ^ | 91 ^ | 90 ^ |
Numbers in bold indicate percentage change >100, ^ indicates that the peak occurs within 6 h post-administration, and a * within 6–12 h post-administration.