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. 2023 Apr 21;13(8):1424. doi: 10.3390/ani13081424

Table 1.

Individual peak increase (%) in urine glucocorticoid metabolite concentrations (uGCM, ng/mg creatinine) within the first 48 h post-injection for 5 male and 5 female naked mole-rats (Heterocephalus glaber) which received a low (20 ug/100 g) or high (60 ug/100 g) dose in relation to individual baseline (EIA specific median of all values before and 48 h after administration).

Dose ID EIA
Cortisol Corticosterone 5α-Pregnane Oxoaetio Oxoaetio
Cholanolone I Cholanolone II
Low F1 −42 −7 40 ^ 174 ^ 11
F2 60 ^ −23 * 46 * 26 * 38 *
F3 325 193 19 130 * −23 *
High F5 29 −13 −15 −5 170
F6 106 * 105 * −2 * 28 * 71 *
Low M1 17 ^ 69 ^ 115 ^ −5 ^ 26
M2 4 * −58 * 131 * 88 * 88 *
M3 1545 ^ 457 ^ 338 ^ 424 ^ 367 ^
High M4 261 91 295 ^ 73 ^ 71
M5 995 ^ 612 ^ 113 ^ 91 ^ 90 ^

Numbers in bold indicate percentage change >100, ^ indicates that the peak occurs within 6 h post-administration, and a * within 6–12 h post-administration.