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. 2023 Apr 21;13(8):1424. doi: 10.3390/ani13081424

Table 3.

Validation studies which investigated dose-dependent response in ACTH challenge test and respective species.

Species Dose EIA Citation
Cattle
(Bos taurus taurus)
0.25 mg, 0.5 mg, and 1 mg 11-oxoetiocholanolone I [41]
Mice
(Mus musculus f. domesticus)
20 μg and 60 μg/100 g 5α-pregnane-3β,11β,21-triol-20-one EIA [3]
Black-tailed prairie dogs (Cynomys ludovicianus) * 4 μg and 12 μg/100 g Cortisol- and Corticosterone- EIAs [43]
Eastern rock sengis (Elephantulus myurus) ` 20 μg and 60 μg/100 g 5α-pregnane-3β,11β,21-triol-20-one EIA [42]

* Reported as 4 IU and 12 IU/kg, ` Reported as 0.2 and 0.6 μg/g.