Table 1.
Characteristics of patients with CPE infection according to colonization and acquisition (n = 77).
| Characteristic | Total (n = 77) |
Colonization (n = 51) |
Acquisition (n = 26) |
p-Value | ||||
|---|---|---|---|---|---|---|---|---|
| Age (median, interquartile range) | 77 (67.0–84.0) | 80.0 (71.5–85.0) | 71.5 (65.3–79.8) | |||||
| <70 years | 23 | (29.9) | 11 | (21.6) | 12 | (46.2) | 0.036 | |
| ≥70 years | 54 | (70.1) | 40 | (78.4) | 14 | (53.8) | ||
| Sex | ||||||||
| Male | 41 | (53.2) | 24 | (47.1) | 17 | (65.4) | 0.152 | |
| Female | 36 | (46.8) | 27 | (52.9) | 9 | (34.6) | ||
| Hospitalization history at other hospitals within 3 months | ||||||||
| Yes | 54 | (70.1) | 41 | (80.4) | 13 | (50.0) | 0.009 | |
| No | 23 | (29.9) | 10 | (19.6) | 13 | (50.0) | ||
| Admission route | ||||||||
| ER | 33 | (42.9) | 25 | (49.0) | 8 | (30.8) | 0.026 | |
| Ward | 35 | (45.5) | 24 | (47.1) | 11 | (42.3) | 0.692 | |
| ICU | 9 | (11.7) | 2 | (3.9) | 7 | (26.9) | 0.003 | |
| Comorbidity | ||||||||
| Yes | 70 | (90.9) | 47 | (92.2) | 23 | (88.5) | 0.68 | |
| No | 7 | (9.1) | 4 | (7.8) | 3 | (11.5) | ||
| Type of specimen | ||||||||
| Rectal swab (stool) | 52 | (67.5) | 37 | (72.5) | 15 | (57.7) | 0.21 | |
| Ect a | 25 | (32.5) | 14 | (27.5) | 11 | (42.3) | ||
| Bacterial species | ||||||||
| Klebsiella pneumoniae | 60 | (77.9) | 42 | (82.4) | 18 | (69.2) | 0.07 | |
| Escherichia coli | 14 | (18.2) | 9 | (17.6) | 5 | (19.2) | ||
| Citrobacter freundii | 2 | (2.6) | 0 | (0.0) | 2 | (7.7) | ||
| Citrobacter amalonaticus | 1 | (1.3) | 0 | (0.0) | 1 | (3.8) | ||
| Carbapenemase-gene | ||||||||
| KPC | 69 | (89.6) | 48 | (94.1) | 21 | (80.8) | 0.07 | |
| NDM | 5 | (6.5) | 2 | (3.9) | 3 | (11.5) | ||
| OXA-48 | 1 | (1.3) | 1 | (2.0) | 0 | (0.0) | ||
| NDM and OXA-48 | 2 | (2.6) | 0 | (0.0) | 2 | (7.7) | ||
Data are presented as n (%). CPE, carbapenemase-producing Enterobacteriaceae; ER, emergency room; ICU, intensive care unit; KPC, Klebsiella pneumoniae carbapenemase; NDM, New Delhi metallo beta-lactamase; OXA-48, oxacillinase-48. a Ect (sputum, urine, wound (pus), body fluid, and blood).