Table 2.
Treatment characteristics and clinical outcomes.
| Variable | Pre-Intervention (n = 211) |
Post-Intervention Group 1 (n = 101) | Post-Intervention Group 2 (n = 228) | p-Value |
|---|---|---|---|---|
| Inpatient antibiotics, n (%) | ||||
| Ampicillin | 2 (<1) | 23 (23) | 73 (32) | <0.001 |
| Amoxicillin | 1 (<1) | 10 (10) | 11 | 0.003 |
| Ceftriaxone | 130 (62) | 39 (39) | 98 (43) | <0.001 |
| Cefdinir | 2 | 1 (1) | - | - |
| Azithromycin | 26 (12) | 6 (6) | 10 (4) | <0.001 |
| Clindamycin | 2 | 1 (1) | 6 | 0.504 |
| Combination therapy | 47 (22) | 21 (21) | 24 (11) | 0.003 |
| None | 1 | - | 2 | - |
| Other | - | - | 5 | - |
| Discharge antibiotics, n (%) | ||||
| Amoxicillin | 28 (13) | 48 (48) | 106 (46) | <0.001 |
| Amoxicillin/clavulanate | 8 (4) | 18 (18) | 47 (21) | <0.001 |
| Cefdinir | 99 (47) | 9 (9) | 11 (5) | <0.001 |
| Azithromycin | 32 (15) | 11 (11) | 14 (6) | 0.008 |
| Clindamycin | 2 (<1) | 3 (3) | 10 (4) | 0.09 |
| Levofloxacin | - | 1 (1) | 4 (2) | - |
| Combination therapy | 35 (17) | 10 (10) | 14 (6) | 0.002 |
| Other | - | - | 4 (2) | - |
| None (completed inpatient) | 7 (3) | - | 25 (11) | - |
| Antibiotic de-escalation performed, n (%) | 6 (3) | 24 (24) | 50 (22) | <0.001 |
| Duration of antibiotic therapy, median (IQR) | 10 (7–10) | 10 (9–11) | 8 (7–10) | <0.00001 |
| Length of stay, mean (SD) | 4.90 (0.87) | 2.07 (0.26) | 1.92 (0.09) | 0.005 |
| 30-day readmission, n (%) | 4 (2) | 7 (7) | 12 (5) | 0.076 |
IQR = interquartile range; SD = standard deviation.