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. 2023 Apr 2;12(4):860. doi: 10.3390/antiox12040860

Table 1.

Inhibitors of lipid oxidation reactions.

Type Mode of Action Examples
“Metal scavenger” Chelates metal ions such as copper and iron,
forming inactive complexes
Chelating agents such as EDTA, citric acid,
phospholipids, polyphosphates
“Oxygen scavenger” Reacts with oxygen; reduces oxygen Ascorbic acid, ascorbyl-palmitate
Antioxidant (AH) Interrupts propagation stages in the case of oxidation reactions; donates a hydrogen atom Phenolic compounds such as BHA, BHT, TBHQ, PG, tocopherols, hydroxytyrosol, caffeic acid, carnosol, etc.
Reducing agents (RSH) Regenerates phenols (synergism) Ascorbic acid
Enzymatic antioxidant Removes dissolved oxygen or oxidative species Superoxide dismutase, glutathione peroxidase, glucose-oxidase-catalase
Antioxidants with multiple functions Regenerates primary antioxidants chelated with metals; reduces hydroperoxides Phospholipids (phosphatidyl-ethanol amine-
fish oil), products of the Maillard reaction
Methyl-silicone and ethylidene phytosterols They prevent oxidative polymerization in
heated oils
Polydimethylsiloxane, citrostadienol