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. 2023 Mar 30;12(4):679. doi: 10.3390/antibiotics12040679

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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BAM as a promising therapeutic target. The essential role of BAM makes it a promising target for both the development of vaccines and for the discovery of new antibiotics. Regions of BAM that have been successfully targeted are indicated in black, with other interactions that additionally be targeted are indicated in red. Given that BAM is known to be highly dynamic, intermediate states during function would present additional interactions that may also be targeted to disrupt function.