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. 2023 Mar 25;12(4):803. doi: 10.3390/antiox12040803

Figure 9.

Figure 9

A schematic depiction of the protective potential of LT against VCR-induced neuropathy in rats. VCR increased the levels of MDA, NO, MPO, Ca2+, TNF-α, IL-1β, IL-6, and caspase-3, and reduced the GSH, SOD, CAT, and IL-10 levels in rat sciatic nerves. In this study, LT was found to significantly reduce VCR-induced oxidative stress, increase antioxidative strength, and reduce neuroinflammatory activity and apoptosis markers against VCR-induced neuropathy.