Akt |
AKT serine/threonine kinase 1 |
ATM |
Ataxia telangiectasia-mutated kinase |
ATR |
Ataxia telangiectasia and Rad3-related kinase |
ATRX |
Alpha-thalassemia/mental retardation x-linked chromatin remodeller |
CDK4 |
Cyclin-dependent kinase 4 |
c-Myc |
Cellular myelocytomatosis |
GIC50
|
50% growth inhibitory concentration |
KO |
Knockout |
MAP |
Methotrexate, doxorubicin and cisplatin |
MAPK |
Mitogen-Activated Protein Kinase |
MDM2 |
E3 ubiquitin-protein ligase MDM2 |
mTOR |
Mammalian target of rapamycin |
OS |
Osteosarcoma |
p53 |
Tumour suppressor protein 53 |
Pol I |
RNA Polymerase I |
PI3K |
Phosphoinositide 3-kinase |
rDNA |
Ribosomal DNA |
RB1 |
Retinoblastoma 1 |
SL-1 |
Selective factor 1 |
tIC50
|
50% transcription inhibitory concentration |
TP53
|
p53 gene |
TSC |
Tuberous Sclerosis Complex |
UBF |
Upstream binding factor |