Table 2:
Distribution of high and low ten–year risk of fracture
| Variable | Early menopause (n = 268) | Typical menopause (n = 717) | P-value | All (n = 985) |
|---|---|---|---|---|
| MOF FRAX – BMD median (range) | 6.70 (1.80–31.00) | 6.90 (1.80–46.00) | 0.758a | 6.80 (1.80–46.00) |
| high risk | 13 (4.9%) | 35 (4.9%) | 0.984b | 48 (4.9%) |
| low risk | 255 (95.1%) | 682 (95.1%) | 937 (95.1%) | |
| MOF FRAX + BMD median (range) | 6.50 (1.90–43.00) | 6.20 (1.40–59.00) | 0.075a | 6.30 (1.40–59.00) |
| high risk | 15 (5.6%) | 27 (3.8%) | 0.206b | 42 (4.3%) |
| low risk | 253 (94.4%) | 690 (96.2%) | 943 (95.7%) | |
| HIP FRAX – BMD median (range) | 1.85 (0.10–64.00) | 1.80 (0.10–33.00) | 0.874a | 1.80 (0.10–64.00) |
| high risk | 81 (30.2%) | 218 (30.4%) | 0.956b | 299 (30.4%) |
| low risk | 187 (69.8%) | 499 (69.6%) | 686 (69.6%) | |
| HIP FRAX + BMD median (range) | 1.60 (0.00–32.00) | 1.30 (0.00–54.00) | 0.004a | 1.30 (0.00–54.00) |
| high risk | 73 (27.2%) | 162 (22.6%) | 0.128b | 235 (23.9%) |
| low risk | 195 (72.8%) | 555 (77.4%) | 750 (76.1%) |
a
Mann-Whitney U test;
b
χ2 – chi-squared test.
Note: For hip fracture, high risk is indicated by a ≥3% ten–year fracture probability.
For MOF fracture, high risk is indicated by a ≥20% ten–year fracture probability.
FRAX MOF − BMD = FRAX score for major osteoporotic fracture without bone mineral density (BMD).
FRAX MOF + BMD = FRAX score for major osteoporotic fracture with BMD.
FRAX HIP − BMD = FRAX score for hip fracture without BMD.
FRAX HIP + BMD = FRAX score for hip fracture with BMD