Table 2.

The list of proteins among the 295 identified human fallopian tube epithelial (hFTE) sEV proteins with known functions in cancer progression and development.

Protein Name	Gene ID	Function	Source
CD44 antigen	CD44	Induce cell proliferation, increase cell survival and cellular motility	Senbanjo, L. (2017) [51]
Ras-related nuclear protein	RAN	Promote membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion	Zaoui, K. (2019) [52]
Integrin beta	ITGB1	Promote ovarian tumor progression and metastasis	Akinjiyan, F. (2022) [53]
S100 calcium binding protein A6	S100A6	Predict peritoneal tumor burden and is associated with advanced stage in ovarian cancer	Wei B. (2009) [54]
Versican core protein	VCAN	Modulate cell adhesion, proliferation, apoptosis, angiogenesis, invasion, and metastasis	Russo, A. (2022) [27]
Periostin	POSTN	Ovarian cancer migration and adhesion, wound healing	Yue, H (2021) [55]
The Ras homologous (Rho) protein	RHOs	Promote ovarian cancer progression and chemoresistance	Jeong, K.J. (2012) [56] Sharma, S. (2014) [57]
Transforming growth factor, beta-induced	TGFBI	Promote ovarian cancer migration and contributes to an Immunosuppressive Microenvironment	Lecker S.M.L. (2021) [58]
Aldehyde dehydrogenase 1A1	ALDH1A1	ALDH1A1 maintains ovarian cancer stem cell-like properties by altered regulation of cell cycle checkpoint and DNA repair network signaling	Meng, E. (2014) [59]
Lysosome-associated membrane glycoprotein 2	LAMP2	Regulate lysosomal stability as well as in autophagy	Eskelinen, E. (2002) [60]
Ras-related protein Rap-1b	RAP1B	The member of RAS oncogene family, promotes ovarian cancer metastasis via notch signaling	Lu, L (2016) [61]
Ras-related protein Rap-1A	RAP1A
Fibronectin	FN1	Promote ovarian cancer invasion and metastasis through an α5β1-integrin/c-Met/FAK/Src-dependent signaling pathway, transducing signals through c-Met in an HGF/SF-independent manner	Lengyel, E (2010) [62]