Table 1.
Main fungal forms in the clinical practice and sensitivity to antifungal treatments are described in the table. High: High sensitivity; Medium: Intermediate sensitivity; Low: Low sensitivity.
| Main Fungal Forms in the Clinical Practice | Sensitivity to Main Antifungal Treatments | ||||||
|---|---|---|---|---|---|---|---|
| Polyene | Triazoles | Echinocandin | |||||
| Amphotericin B | Itraconazole | Voriconazole | Posaconazole | Isavuconazole | Fluconazole | Anidulafungin Caspofungin Micafungin |
|
| Aspergillus fumigatus | low | low | high | medium | medium | low | high |
| Aspergillus hiratsukae | high | high | high | high | medium | Low | high |
| Aspergillus lentulus | low | low | low | medium | medium | low | high |
| Candida spp. | medium (not against C. krusei, C. lusitania) | medium/high | species-dependent | medium | species-dependent | species-dependent | medium/high |
| Fusarium spp. | medium | no activity/low | species-dependent | medium | low | low | low |
| Fusarium solani | medium | low | low | low | low | low | low |
| Lamentospora prolificans | low | low | low/medium | low | low | low | low |
| Mucorales | medium | no activity/low | no activity/low | species-dependent | species-dependent | low | low |