Table 2.

Summary of in vivo studies.

Study	Reference	Pharmacological Treatment	Effect
He et al., 2022	[48]	Nimotuzumab	Inhibit cell proliferation and promote apoptosis in OSCC, increasing the cure rate.
He et al., 2019	[49]	Metformin + 4SC-202	Inhibit cancer cell growth and induce intrinsic cell apoptosis through increasing ΔNp63 ubiquitination and degradation.