α-syn |
alpha-synuclein |
Aβ |
amyloid-beta |
AD |
Alzheimer’s disease |
ALOX15 |
arachidonate 15-lipoxygenase |
ALS |
amyotrophic lateral sclerosis |
APP |
amyloid precursor protein |
ARE |
antioxidant response element |
ASC |
apoptosis-associated speck-like protein containing a CARD |
ATP |
adenosine triphosphate |
Bach1 |
BTB and CNC homology 1 |
BECN1 |
beclin 1 |
BMP |
bone morphogenetic protein |
CNS |
central nervous system |
COX2 |
cyclooxygenase-2 |
CRB |
CREB-binding protein |
DAMP |
damage-associated molecular pattern |
DcytB |
duodenal cytochrome B |
DMT1 |
divalent metal transporter 1 |
e−
|
electron |
EMT |
epithelial–mesenchymal transition |
Fe2+
|
ferrous iron |
Fe3+
|
ferric iron |
FPN1 |
ferroportin 1 |
FTH1 |
ferritin heavy chain |
FTL |
ferritin light chain |
GSH |
glutathione |
4-HNE |
4-hydroxy-2,3-trans-nonenal |
HEPH |
hephaestin |
HERC2 |
HECT domain and RCC1-like domain 2 |
HMOX-1 |
heme oxygenase |
H2O2
|
hydrogen peroxide |
HO-1 |
heme oxygenase-1 |
IκB-α |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor alpha |
IKKα |
IκB kinase alpha |
IL |
interleukin |
iNOS |
inducible nitric oxide synthase |
IRE |
iron-responsive element |
IRP |
iron-regulatory protein |
KEAP1 |
Kelch-like ECH-associated protein 1 |
LC3 |
microtubule-associated protein 1A/1B-light chain 3 |
LIP |
labile iron pool |
LPS |
lipopolysaccharide |
MCP1 |
monocyte chemoattractant protein 1 |
MIP2 |
macrophage inflammatory protein 2 |
MPTP |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
MyD88 |
myeloid differentiation primary response protein 88 |
NAD+
|
nicotinamide adenine dinucleotide |
NCOA4 |
nuclear receptor coactivator 4 |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
NFT |
neurofibrillary tangle |
NIK |
NF-κB-inducing kinase |
NLRP |
nucleotide-binding domain and leucine-rich repeat and pyrin domain-containing protein |
NOX2 |
nicotinamide adenine dinucleotide phosphate oxidase 2 |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
Nrf2 |
nuclear factor erythroid 2-related factor 2 |
•OH |
hydroxyl radical |
OS |
oxidative stress |
P |
phosphorylation |
P2X7R |
P2X purinergic receptor 7 |
p53 |
tumor protein P53 |
PCBP |
poly(rC)-binding protein |
PD |
Parkinson’s disease |
PGC-1α |
peroxisome proliferator-activated receptor gamma coactivator 1-alpha |
PIR |
pirin |
PPAR |
peroxisome proliferator-activated receptor |
PGs |
prostaglandins |
PUFA |
polyunsaturated fatty acid |
ROS |
reactive oxygen species |
SIRT1 |
silent information regulator factor 2-related enzyme 1 |
STAT3 |
signal transducer and activator of transcription 3 |
Steap3 |
six-transmembrane epithelial antigen of prostate family member 3 |
SMAD |
suppressor of mothers against the decapentaplegic |
Tf |
transferrin |
TfR |
transferrin receptor |
TLR |
Toll-like receptor |
TNF-α |
tumor necrosis factor-α |
TNFR |
tumor necrosis factor receptor |
TOM20 |
translocase of the outer membrane 20 |
Ub |
ubiquitin |
UPS |
ubiquitin–proteosome system |
UTR |
untranslated region |
Zn2+
|
zinc ion |