Table 1.
Clinical features of offspring of patients with early acute myocardial infarction and HS.
| Variables | Offspring of Patients with Early Acute Myocardial Infarction (N = 46) |
Healthy Subjects (N = 86) |
p Value |
|---|---|---|---|
| Age (years) | 13.76 ± 6.858 | 11.73 ± 5.779 | 0.092 |
| Gender (M/F) | 26/20 (56.5/43.5%) | 58/28 (67.4/32.6%) | 0.214 |
| Serum TXB2 a (pg/mL) | 429.35 ± 222.859 | 243.01 ± 102.713 | <0.001 |
| 8-iso-PGF2α-III (pg/mL) | 352.46 ± 163.576 | 144.84 ± 83.649 | <0.001 |
| sP-Selectin (ng/mL) | 26.13 ± 6.45 | 18.50± 4.30 | <0.001 |
| sNOX-2-dp b (pg/mL) | 33.83 ± 10.369 | 20.35 ± 9.166 | <0.001 |
| H2O2 µM | 34.33 ± 6.06 | 26.09 ± 5.17 | <0.001 |
| NO bioavailability µM | 28.72 ± 7.24 | 47.28± 16.54 | <0.001 |
| Serum LPS c (pg/mL) | 33.33 ± 7.242 | 16.43 ± 9.094 | <0.001 |
| Serum zonulin (ng/mL) | 2.1533 ± 0.805 | 1.566 ± 0.666 | <0.001 |
| Total Cholesterol (mg/dL) | 190.67 ± 49.58 | 170.69 ± 49.58 | 0.017 |
| Glycemia (mg/dL) | 86.13 ± 6.27 | 88.96 ± 11.07 | 0.136 |
| Systolic blood pressure (mmHg) | 110.78 ± 12.74 | 110.02 ± 9.77 | 0.746 |
| Diastolic blood pressure (mmHg) | 63.41 ± 9.66 | 66.79 ± 13.44 | 0.144 |
| BMI d | 21.61 ± 4.38 | 20.76 ± 4.30 | 0.285 |
a TXB2, Thromboxane B2; b sNOX-2-dp soluble NADPH oxidase-type 2 derived peptide; c LPS, lipopolysaccharide; d BMI, body mass index.