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. 2023 Apr 6;12(4):558. doi: 10.3390/biology12040558

Table 6.

Cytoprotective effect of humanin, N/A is not applicable.

Article Study Design Population Outcome Measures
Alsanousi, N. et al. (2016) [125] In vitro study N/A Inhibitory effect against amyloid-β fibrillation of humanin
Zaman, F. et al. (2019) [126] In vitro study N/A Humanin regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment
Qin, Q. et al.
(2018) [129]
In vivo study Mouse Effect of exogenous humanin to prevent and reverse cardiac fibrosis and apoptosis in the aging heart
Liu, C. et al.
(2019) [106]
In vivo study Human Expression levels of humanin and MOTS-C in skeletal muscle and serum levels in CKD