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. 2023 Mar 27;11(4):1016. doi: 10.3390/biomedicines11041016

Table 2.

Studies of FMT in IBD.

Borody T.J. et al. 2003 [56] 6 patients with severe, recurrent symptoms of UC
FMT with enemas for 5 days
Complete reversal of symptoms was achieved in all patients by 4 months post-FMT
Kunde S. et al. 2013 [57] 10 pediatric patients with mild-to-severe UC
FMT with enemas for 5 days
Patients achieved clinical remission at 1 week after FMT
Gianluca Ianiro, et al. 2014 [3] 133 patients (77 with UC, 53 with CD and 3 indefinite BDI)
42 patients received FMT via upper routes (nasogastric or naso-jejunal tube and gastroscopy),
20 patients through enema
23 through colonoscopy
11 patients had FMT infusions via both upper and lower routes for IBD resistant to therapy
FMT obtained a reduction of 71% in symptoms
Sudarshan Paramsothy, et al. 2017 [61] 555 patients with UC (42 studies reporting on FMT in 2017)
Clinical remission after FMT in 201 cases
Sudarshan Paramsothy, et al. 2019 [62] 81 patients with active UC in a double blind trial
FMT for active UC and stool samples from donors
FMT group was associated with specific bacteria and metabolic pathways with induction of remission
Samuel P. Costello et al. 2019 [72] 73 adults with UC
FMT via colonoscopy followed by 2 enemas over 7 days
38 Donor FMT
35 Autologous FMT
Wang, Y. et al. 2020 [29] 16 active UC patients enrolled
87.5% (n= 14) patients achieved clinical response to FMT