Table 2.
Borody T.J. et al. 2003 [56] | 6 patients with severe, recurrent symptoms of UC FMT with enemas for 5 days Complete reversal of symptoms was achieved in all patients by 4 months post-FMT |
Kunde S. et al. 2013 [57] | 10 pediatric patients with mild-to-severe UC FMT with enemas for 5 days Patients achieved clinical remission at 1 week after FMT |
Gianluca Ianiro, et al. 2014 [3] | 133 patients (77 with UC, 53 with CD and 3 indefinite BDI) 42 patients received FMT via upper routes (nasogastric or naso-jejunal tube and gastroscopy), 20 patients through enema 23 through colonoscopy 11 patients had FMT infusions via both upper and lower routes for IBD resistant to therapy FMT obtained a reduction of 71% in symptoms |
Sudarshan Paramsothy, et al. 2017 [61] | 555 patients with UC (42 studies reporting on FMT in 2017) Clinical remission after FMT in 201 cases |
Sudarshan Paramsothy, et al. 2019 [62] | 81 patients with active UC in a double blind trial FMT for active UC and stool samples from donors FMT group was associated with specific bacteria and metabolic pathways with induction of remission |
Samuel P. Costello et al. 2019 [72] | 73 adults with UC FMT via colonoscopy followed by 2 enemas over 7 days 38 Donor FMT 35 Autologous FMT |
Wang, Y. et al. 2020 [29] | 16 active UC patients enrolled 87.5% (n= 14) patients achieved clinical response to FMT |