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Mice fed with an HFD and treated with metformin (MET) or Morus alba L. extract (MAE) presented lower hypertrophy of adipocytes compared to HFD-untreated mice. (A) Adipocyte area quantification. (B) Representative images of adipocyte area of the different groups of study. Yellow arrows refer to the presence of immune cells. Data are expressed as means ± SEM (n = 8). Groups with different letters statistically differ (p < 0.05). SD: standard diet; HFD: high-fat diet.
