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. 2023 Apr 21;12(4):978. doi: 10.3390/antiox12040978

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Volcano plot and LEfSe analysis showed specific bacteria increase depending on the administered treatment. Morus alba L. extract (MAE) presented a statistically significantly higher abundance of Pseudomonas. (A) Volcano plot showing differential abundance taxa of Morus alba L.-treated mice vs. metformin (MET)-treated mice. (B) Linear discriminant analysis (LDA) effect size (LEfSe) plot of taxonomic biomarkers (p value = 0.05 and LDA value = 3) (n = 8). SD: standard diet; HFD: high-fat diet.