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. 2023 Apr 11;10(4):464. doi: 10.3390/bioengineering10040464

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Histopathologic changes upon PDT treatment. (A) Histopathology of untreated and PDT-treated CDX tumors of different sarcoma subtypes. Tumors were harvested 24 h after PDT treatment. Ewing sarcoma: M4M53, H8T8, TC-32; myxoid liposarcoma: mLPS-SN1; endometrial stromal sarcoma: ESS-SN1; osteosarcoma: E5K5; myxofibrosarcoma: MFS-SN1. (B) Pooled effect of PDT on tumor regression. Details on composition (number of untreated/number of PDT treated): M4M53 (1/3); H8T8 (1/2); E5K5 (6/2); ESS-SN1 (4/3); mLPS-SN1 (3/4); MFS-SN1 (5/3); TC-32 (6/4).