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Effects of ERK1/2 inhibition by U0126 co-treatment on SE-induced neuronal damage in CA1 neurons of EGCG-treated rats. Compared with the vehicle, U0126 co-treatment abolished the protective effect of EGCG on SE-induced neuronal degeneration. (A) Representative FJB-positive-degenerating CA1 neurons following SE. (B) Quantification of the number of FJB-positive neurons (* p < 0.05 vs. vehicle co-treatment; n = 7 rats, respectively).
