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. 2023 Apr 13;12(4):923. doi: 10.3390/antiox12040923

Figure 3.

Figure 3

KDELC2 suppression decreased the level of ER stress in glioblastoma. (A) The shKDELC2-transfected GBM8401 and U87MG inhibited ER stress-related factor expression. (B) The application of salubrinal resulted in no difference in the ER stress in shKDELC2-transfected glioblastoma cells. (C) The administration of GSK2606414 in shKDELC2-transfected glioblastoma cells revealed no difference in ER stress-related factors expression. (D) The addition of salubrinal and GSK2606414 in shLuc and shKDELC2 both decreased HUVEC proliferation. Bars, means ± SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.001; ##, p < 0.01; ###, p < 0.001; ns—non-significant.