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. 2023 Apr 13;13(4):474. doi: 10.3390/bios13040474

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

RPS—aptasensors based on aptamer folding for biomolecule detection. (A) Aptamer-based sensor for 17β-estradiol detection via the size contraction response of aptamer-functionalized nanoparticles, reproduced with permission from [104]. Copyright 2014 Biosensors and Bioelectronics. (B) AptaTRPS based on aptamer-tagged nanoparticles to monitor the interaction between the aptamer and protein, reproduced with permission from [105]. i, ii, iii represent bare NPs, NPs modified by aptamers, and modified NPs interacted with targets respectively. Copyright 2014 American Chemistry Society. (C) Size-multiplexed detection of biomolecules using aptamers and TRPS, reproduced with permission from [106]. Copyright 2015 Biosensors and Bioelectronics.